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In 2026, the United States Chief Justice's son was inflicted with this disease. This was the first known case in the United States. Daryan Crescend once attempted to smuggle the only known cure for the disease, which was derived from the illegal Borginian cocoon, into the country. However, Interpol seemed to catch wind of this plan, and sent Borginian agent Romein LeTouse to investigate the famed singer, Lamiroir and her accompanying pianist, Machi Tobaye, the latter of which was an accomplice of Crescend's. This case lead to LeTouse's demise. Crescend was tried and convicted for this murder, before he could get the cure to the chief's son.
The suffix "-itis" is used for medical conditions that are characterised by inflammation (e.g. arthritis), suggesting that this may be one of the symptoms of Incuritis. If this is the case, then the name "Incuritis" itself would roughly mean "incurable inflammation". However, since "-itis" is quite often used as a generic suffix for various fictional diseases, it is entirely possible that inflammation has nothing to do with the disease at all.